Keyword: migration
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Tracking of cancer cell-matrix interactions in a fully controllable 3D fiber system
The mechanical, geometrical and chemical properties of the 3D fibrous extracellular matrix play a key role in cancer initiation and progression, by controlling the movement and fate of tumor cells as well as surrounding fibroblasts, immune or endothelial cells. A strong emphasis has been put recently on the development of matrices with controllable fiber properties…