Skill: python
-
Multicolor multifocus microscopy for multidimensional single molecule imaging
The ability to control the wavefront at the output of an imaging system allows to correct the imaging system optical aberration but also to impose a controlled deformation to encode specific information in the recorded images. Diffractive optical elements (DOE) provide an efficient mean to manipulate light. When placed in the back focal plane of…
-
Loop extrusion as a writer of chromatin memory
We are interested in the way chromatin organizes inside the nucleus, and in particular how cellular activities define chromatin conformation and how this can affect the transcriptional regulation. In this project the focus is loop extrusion, a process that has been proposed to control transcription, and consists in the activity of a molecular motor (cohesin) that…
-
Self-organization of chemotactic cell assemblies
Understanding the self-organization of living systems is one of the biggest conceptual challenges of the present century. A generic mechanism that drives such organization is interaction among the individual elements — which may represent cells, bacteria, or even enzymes — via chemical signals. The ability of an individual cell to follow a gradient of chemicals…