Keyword: cryo-electron tomography
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Deciphering protein-induced invagination at sub-nanometric resolution by cryo-electron tomography
Cryo-electron microcopy is revolutionising our vision of proteins and the cell (Nobel Prize 2017). One approach, known as isolated particle analysis, makes it possible to build atomic models of purified and homogeneous. At the same time, cryo-tomography (cryo-ET) is being developed to obtain molecular models of more complex samples, in vitro reconstituted or within cells…