Keyword: confocal microscopy
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Local actin polymerization on lipid membrane driven by surface nanotopography
Recent studies have shown that cells are able to sense small topographical features and to respond to them by locally assembling different types of actin-based structures (actin-patches, podosomes) on these textures. These structures influence the motility of the cells, adhering or not to the surface (Fig.1A, Left), and the localization of podosomes in macrophages. Cell…